Member, GRU Cancer Center
Assistant Professor of Medicine, Section of Hematology/Oncology
1120 15th Street, BAA-5407
Sangmi Kim, Ph.D. is an Assistant Professor in the Department of Medicine, Section of Hematology/Oncology, and a member of the Cancer Center at Georgia Regents University. She received her BHE degree from Department of Food and Nutrition, Seoul National University, Korea in 1999, an MS degree from Department of Community Health, University of Illinois, Urbana-Champaign in 2004, and her from the Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill in 2007.
Dr. Kim’s primary research interest is in the etiology of cancer, particularly colorectal and breast cancer. During the past few years, her research has focused on the role of inflammation in carcinogenesis, studying various modifiable exposures that may influence inflammation and subsequent cancer risk such as diet and obesity. She has also invested considerable effort in integrating rapidly developing techniques of molecular biology in cancer epidemiologic research to identify and validate novel biomarkers that can refine exposure classification, validate the effect of intervention, and predict cancer risk.
Ongoing projects in Dr. Kim’s laboratory include: 1) a study of telomere length in blood in relation to genetic variants of epigenetic regulators; and 2) a study of prostaglandin E2 and 15 urinary estrogen metabolites as a potential biomarker for breast cancer in postmenopausal women. These projects are being conducted in collaboration with investigators at the National Institute of Environmental Health Sciences (NIEHS), using data from a national cohort of 50,884 women with a family history of breast cancer.
Dr. Kim is also developing a research program that studies the role of immune tolerance in the development and progression of cancer. Increasing evidence indicates that the immune response is a host protection mechanism to recognize and control tumor growth. However, the immune response deteriorates with aging, probably due to the accumulation of chronic antigenic stresses. Accelerated immune aging, which results from higher antigenic burden from early life, may also provide a clue to understand socioeconomic disparities in cancer incidence and survival.