1120 15th Street, BAE 2571C
Augusta, GA 30912
Office: (706) 721-2771
Dr. Sharma earned his M.B,B.S. from Indira Gandhi Medical College, Shimla, Himachal Pradesh (1987), followed by M.D. from the All India Institute of Medical Sciences, New Delhi (1992) where he performed his thesis on gliomas. He received his residency training at the NYU Medical Center in New York (1999). Dr. Sharma is board-certified in Anatomic Pathology and Neuropathology, and in his primary role serves as a diagnostic surgical pathologist and neuropathologist. In the latter capacity, he provides pathologic diagnosis on CNS neoplasia and their mimics, including vascular and demyelinating disorders, epilepsy resections, and neuromuscular disorders, as well as autopsy diagnosis of conditions such as stroke and neurodegeneration.
Dr. Sharma’s primary research interest is in pathology and biology of CNS neoplasia particularly gliomas and conditions underlying epilepsy. He has collaborated with well-known physician-scientists, neuroscientists and geneticists. His efforts have included clinicopathologic characterization, and evaluating molecular prognostic/predictive markers aiming to improve the outcome of CNS disorders utilizing immunohistochemistry, image analysis, FISH and comparative genome hybridization. He plans to further his research efforts in alignment with the current leadership priorities in Pathology (Dr. Rojiani), Neurooncology (Dr. Rixe) and Molecular Oncology (Dr. Cowell) at the GHSU Cancer Center.
Aggarwal G, Jackson L, Sharma S: Primary combined small cell carcinoma of larynx with lateralized histologic components and corresponding side-specific neck nodal metastasis: Report of a unique case and review of literature. Int J Clin Exp Pathol 2011;4(1):111-117.
Yuan J, Sharma N, Choudhri H, Figueroa R, Sharma S. Intraventricular dysembryoplastic neuroepithelial tumor in a pediatric patient: Is it the most common extracortical location for DNT? Childs Nerv Syst. 2010 Oct 20. [Epub ahead of print]
Silva J, Sharma S, Hughes B, Yu YE, Cowell JK. Homozygous inactivation of the LGI1 gene results in hypomyelination in the peripheral and central nervous systems. J Neurosci Res. 2010 Nov 15; 88(15): 3328-36.
Lober R, Sharma S (co-first author), Bell B, Free A, Figueroa R, Sheils CW, Lee M, Cowell J. Pediatric primary intramedullary spinal cord glioblastoma: Report of two cases, genomic analysis and review of the recent literature. Rare Tumors 2010; 2(3): e48.
Deb P, Sharma S, Hassan KM.Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis. Pathophysiology 2010 Jun;17(3):197-218.
Teng Y, Ren MQ, Cheney R, Sharma S, Cowell JK. Inactivation of the WASF3 gene in prostate cancer cells leads to suppression of tumorigenicity and metastases. Br J Cancer. 2010 Aug 17. [Epub ahead of print]
Abdelsayed RA, Sharma S, Ferguson H. Fibrous cortical defect (nonossifying fibroma) of the mandibular ramus: report of 2 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Aug 5. [Epub ahead of print]
Sharma S, Free A, Mei Y, Peiper SC, Wang Z, Cowell JK. Distinct molecular signatures in pediatric infratentorial glioblastomas defined by aCGH. Exp Mol Pathol. 2010 Oct;89(2):169-74. Epub 2010 Jul 16.
Witcher MR, Park YD, Lee MR, Sharma S, Harris KM, Kirov SA. Three-dimensional relationships between perisynaptic astroglia and human hippocampal synapses. Glia. 2010 Apr;58(5):572-87.
Bollag RJ, Vender JR, Sharma S. Anaplastic meningioma: Progression from atypical and chordoid morphotype with morphologic spectral variation at recurrence. Neuropathology. 2010 Jun;30(3):279-87.